From the editors

Nature Reviews Neuroscience 11, 147 (2010). doi:10.1038/nrn2819

This issue of Nature Reviews Neuroscience contains several articles about aspects of the transmission of information and disease in the nervous system.In his Review on page 188, Benjamin Kaupp compares and contrasts the chemosensory receptors and signalling mechanisms involved in olfaction in

Neural circuits: Out of synch

Nature Reviews Neuroscience 11, 149 (2010). doi:10.1038/nrn2817

Author: Katherine Whalley

Correlated firing in cortical circuits may be weaker than was previously thought.

Neurological disorders: Striking point for stroke

Nature Reviews Neuroscience 11, 150 (2010). doi:10.1038/nrn2814

Author: Monica Hoyos Flight

DAPK1 is a specific cell death signal that is recruited to NMDA receptors and mediates brain damage in stroke.

In Brief

Nature Reviews Neuroscience 11, 150 (2010). doi:10.1038/nrn2820

Neuronal plasticity

Sensory processing: Sensing motion with tact

Nature Reviews Neuroscience 11, 151 (2010). doi:10.1038/nrn2816

Author: Cristian Bodo

A population of neurons in the somatosensory cortex responds specifically to the direction of a moving tactile stimulus.

Techniques: Zebrafish behaviour in profile

Nature Reviews Neuroscience 11, 152 (2010). doi:10.1038/nrn2815

Author: Katherine Whalley

High-throughput screens have been developed to assess the effects of drugs on behaviour in zebrafish.

Neuron–glia interactions: With a little help from glia

Nature Reviews Neuroscience 11, 152 (2010). doi:10.1038/nrn2818

Author: Claudia Wiedemann

D-serine release from astrocytes induces LTP in hippocampal slices.

In Brief

Nature Reviews Neuroscience 11, 153 (2010). doi:10.1038/nrn2821

Development

Protein palmitoylation in neuronal development and synaptic plasticity

Nature Reviews Neuroscience 11, 161 (2010). doi:10.1038/nrn2788

Authors: Yuko Fukata & Masaki Fukata

Protein palmitoylation, a classical and common lipid modification, regulates diverse aspects of neuronal protein trafficking and function. The reversible nature of palmitoylation provides a potential general mechanism for protein shuttling between intracellular compartments. The recent discovery of palmitoylating enzymes — a large DHHC (Asp-His-His-Cys) protein

Overnight alchemy: sleep-dependent memory evolution

Nature Reviews Neuroscience 11, 218 (2010). doi:10.1038/nrn2762-c1

Authors: Matthew P. Walker & Robert Stickgold

Diekelmann and Born offer an elegant and convincing overview of evidence supporting the role of sleep in the consolidation of newly acquired memories (The memory function of sleep. Nature Rev. Neurosci.11, 114–126 (2010)). An

Slow-wave sleep takes the leading role in memory reorganization

Nature Reviews Neuroscience 11, 218 (2010). doi:10.1038/nrn2762-c2

Authors: Susanne Diekelmann & Jan Born

We recently proposed a comprehensive framework for sleep-dependent memory consolidation suggesting that, during slow-wave sleep (SWS), memory representations are transferred from a temporary to a long-term store and thereby undergo reorganization in a process of system consolidation (The memory function of sleep. Nature Rev. Neurosci.

CART peptides: regulators of body weight, reward and other functions

Nature Reviews Neuroscience 11, 218 (2010). doi:10.1038/nrn2806

Author: G. Rogge, D. Jones, G. W. Hubert, Y. Lin & M. J. Kuhar

Nature Reviews Neuroscience9, 747–758 (2008)In figure 4a of the article, the doses of the bilateral CART (cocaine- and amphetamine-regulated transcript) peptide infusions were incorrectly given in milligrams. In both the figure and the legend, the doses should

Abnormal neural oscillations and synchrony in schizophrenia

Nature Reviews Neuroscience 11, 100 (2010). doi:10.1038/nrn2774

Authors: Peter J. Uhlhaas & Wolf Singer

Converging evidence from electrophysiological, physiological and anatomical studies suggests that abnormalities in the synchronized oscillatory activity of neurons may have a central role in the pathophysiology of schizophrenia. Neural oscillations are a fundamental mechanism for the establishment of precise temporal relationships between neuronal responses that

Neurodegeneration: Export disrupts transport

Nature Reviews Neuroscience 11, 74 (2010). doi:10.1038/nrn2796

Author: Leonie Welberg

Inflammation-induced nuclear export of HDAC1 disrupts axonal transport of mitochondria, initiating axonal damage in models of demyelinating diseases.

Synaptogenesis: A new partner for neurexins

Nature Reviews Neuroscience 11, 72 (2010). doi:10.1038/nrn2798

Author: Katherine Whalley

LRRTM2 drives presynaptic and postsynaptic synapse assembly and is a ligand for neurexin 1

In brief

Nature Reviews Neuroscience 11, 76 (2010). doi:10.1038/nrn2800

Sensory systems

In brief

Nature Reviews Neuroscience 11, 75 (2010). doi:10.1038/nrn2801

Visual system

From the editors

Nature Reviews Neuroscience 11, 71 (2010). doi:10.1038/nrn2802

The importance of coordinating activity across neural networks for brain function.

Astroglial networks: a step further in neuroglial and gliovascular interactions

Nature Reviews Neuroscience 11, 87 (2010). doi:10.1038/nrn2757

Authors: Christian Giaume, Annette Koulakoff, Lisa Roux, David Holcman & Nathalie Rouach

Dynamic aspects of interactions between astrocytes, neurons and the vasculature have recently been in the neuroscience spotlight. It has emerged that not only neurons but also astrocytes are organized into networks. Whereas neuronal networks exchange information through electrical and chemical synapses, astrocytes are interconnected through

Neuronal Networks: A hub of activity

Nature Reviews Neuroscience 11, 74 (2010). doi:10.1038/nrn2799

Author: Claudia Wiedemann

GABAergic interneurons were identified as hub cells that trigger network synchronization in the hippocampus.